Polyphenols and gut microbiota: the virtuous interaction




Consumers are adopting a back-to-basics approach to nutrition. This is resulting in people making greater efforts to maximize their intake of fruit and vegetables.

Prevention-over-cure approach to health – consumers are actively researching on how to lead a healthier lifestyle, and on ingredients that can help facilitate this, as they adopt a long-term approach to health.

In the group of prebiotics, polyphenols are probably the most important secondary metabolites produced by the plants. This way, polyphenols could modulate the intestinal microbiota, a role added to their main properties, which are antioxidant and anti-inflammatory.

Polyphenols family counts a large diversity of chemical forms, resulting in different absorption pathways along the digestive tract. 

Many of these polyphenols have low bioavailability, therefore reaching the colon in unaltered form.

Once in the colon, these compounds interact with the intestinal microbes bidirectionally by modulating them and, consequently, releasing metabolites.

These compounds, not only by their structure but also by the resulting metabolites, are a substrate for probiotics. It results in the growth of beneficial bacteria and the reduction of pathogenic bacteria, thereby maintaining host intestinal homeostasis.

Source: [Review] Plamada, D.; Vodnar, D.C; Nutrients 2022, 14, 137.

Oxxynea® is a combination of plant-based extracts providing polyphenols as in the daily consumption of 5 servings of fresh fruit and vegetables. 

It has been formulated to offer a wide spectrum of different polyphenols providing a 24-hour metabolic protection: more than 40 metabolites have been identified at different times in the bloodstream of supplemented subjects (Proprietary clinical study, publication pending).


– Fills the nutritional gap
– Provides the same polyphenol content and antioxidant protection as 5 servings of fruit & vegetables
– Contributes to maintain biological homeostasis to protect the metabolism against day to day challenges
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This website is intended to provide information about Fytexia’s ingredients, used in various dietary supplement products around the world. It is intended to provide information to food supplement professionals and is not designed for the general public. As Fytexia’s ingredients are being marketed in a large number of countries, it is the responsibility of each of our customers to ensure that the use of the ingredient and any claim made in the labeling or advertising of the ingredient comply with the applicable rules and regulations.