Muscle discomfort

TensLess® is a plant-based ingredient formulated to restore physical capacity by reducing muscle soreness and feeling of pain after muscle exertion during daily routines or intense activities. Supported with 1 clinical trial. 900mg/day.

Joint and muscle discomfort affects the worldwide population, without distinction of age or physical practice. It may limit performance for sportsmen or reduce autonomy and increase tiredness for the elderly.

Joint health

Muscle discomfort

Characterization of the active compounds

Formulated from mangosteen, pomegranate, and elderberry extracts, Tensless® delivers xanthones, clinically proven to reduce joint discomfort¹ combined with ellagic acids and anthocyanins for an overall action on soft tissue flexibility.

Active Compounds

Xanthones ≥ 9.5%
Ellagic acid ≥ 13.9%
Anthocyanins ≥ 0.5%

BOTANICAL SOURCES

Mangosteen extract
Pomegranate extract
Elderberry extract

Garcinia mangostana L.
Punica granatum L.
Sambucus nigra L.

FORMULATION

Recommended daily dosage: 900mg

Science supporting TensLess®

The scientific dossier of TensLess® is based on the clinical previous studies on the anti-inflammatory benefits of xanthones (as formulated in Mangoselect®) completed with a dedicated clinical study on muscle soreness improvement.

PRE-CLINICAL STUDY
Mangoselect®

PILOT CLINICAL STUDY
Mangoselect®

DEDICATED PILOT CLINICAL STUDY
TensLess®

Clinical study

Double-blind, randomized, cross-over controlled study²

Location

University of Pavia, Italia

DURATION

Acute study – 5 days

POPULATION

24 subjects
9 elders
15 athletes

INTAKES

CAPSULES
2 x 300 mg/day

PRIMARY OUTCOME

Score on a DOMS (Delayed-Onset Muscle Soreness) rating scale

Delayed Onset Muscle Soreness (DOMS) is the pain and stiffness felt in muscles several hours to days after unaccustomed or strenuous exercise.

Discomfort
Swelling
Loss of strength
Limited range of motion

MEASURE OF MUSCLE SORENESS

Evaluated by visual analogue scale

MODEL OF GENERATION OF MUSCLE SORENESS

Day 1
8 x 8-Repetition Maximum (RM)
8 series of 8 half squats lifting an individualized maximum weight
Day 2 to day 5
Rest

OTHER OUTCOMES

Blood samples: measure of acute and mid-term biomarkers of muscle damage

Muscular protection

TensLess® significantly limits the increase of both acute (myoglobin) and mid-term (creatinine and creatine kinase) biomarkers of muscle damage^3,4 in the supplemented group.

Relief from induced muscle soreness

DOMS scores decreases in the TensLess® group as soon as 1 hour after the muscle stimulation and were lowered by 28% with the supplementation compared to the placebo group. Associated muscle pain also significantly decreases in the TensLess® group, by 35% over the 4 days following the activity.

KEY OUTCOMES

Clinically proven effective in a 5-day supplementation
Acute benefits
Eases joint discomfort, soreness and muscle discomfort
Plant-based ingredient

Applications

Commercial name

TensLess®

COMPOSITION

Mangosteen, pomegranate and elderberry extracts

ACTIVE COMPOUNDS

Ellagic acid ≥ 13.9%
Xanthones ≥ 9.5%
Anthocyanins ≥ 0.5%

RECOMMENDED DOSAGE

900 mg/day

APPLICATIONS

Dietary supplements

OTHERS

No allergen, non-GMO, gluten-free, suitable for vegans

References
1 – Romain C. & cases J.; 2015; Agro Food Industry Hi Tech; 26(3):8-13
2 – Romain C. et al. 2017; Phytother. Res.; 31(11):1739-46
3 – Rodenburg J. B. et al. 1993; J. Appl. Physiol.; 19(2):93-9
4 – Hassan E. S.. 2011; J. Sports Med. Phys Fitness; 51(2):249-54

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Muscle discomfort

Characterization of the active compounds

Active Compounds

BOTANICAL SOURCES

FORMULATION

Science supporting TensLess®

Clinical study

Muscular protection

Relief from induced muscle soreness

KEY OUTCOMES

Applications

Polyphenol concentrates

Prebiotics