Muscle discomfort

Quality
of life

Joint and muscle discomfort affects the worldwide population, without distinction of age or physical practice. It may limit performance for sportsmen or reduce autonomy and increase tiredness for the elderly. 
Joint health
Muscle discomfort

Characterization of the active compounds

Formulated from mangosteen, pomegranate, and elderberry extracts, Tensless® delivers xanthones, clinically proven to reduce joint discomfort1 combined with ellagic acids and anthocyanins for an overall action on soft tissue flexibility. 

Active Compounds

Xanthones          ≥ 9.5%
Ellagic acid         ≥ 13.9%
Anthocyanins    ≥ 0.5%

BOTANICAL SOURCES

Mangosteen extract 
Pomegranate extract 
Elderberry extract 

Garcinia mangostana L.
Punica granatum L. 
Sambucus nigra L.

FORMULATION

Recommended daily dosage: 900mg

Science supporting TensLess®

The scientific dossier of TensLess® is based on the clinical previous studies on the anti-inflammatory benefits of xanthones (as formulated in Mangoselect®) completed with a dedicated clinical study on muscle soreness improvement. 

PRE-CLINICAL STUDY
Mangoselect®

PILOT CLINICAL STUDY
Mangoselect®

DEDICATED PILOT CLINICAL STUDY
TensLess®

Clinical study

Double-blind, randomized, cross-over controlled study2
Location

UCAM, University of Murcia, Spain 

DURATION
Acute study – 5 days
POPULATION

13 subjects 
20-42 years old 
Recreationally active (< 3h of practice/week)

INTAKES

CAPSULES 
2 x 300 mg/day 

PRIMARY OUTCOME
Score on a DOMS (Delayed-Onset Muscle Soreness) rating scale

Delayed Onset Muscle Soreness (DOMS) is the pain and stiffness felt in muscles several hours to days after unaccustomed or strenuous exercise. 

  • Discomfort
  • Swelling
  • Loss of strength
  • Limited range of motion
MEASURE OF MUSCLE SORENESS

Evaluated by visual analogue scale

MODEL OF GENERATION OF MUSCLE SORENESS

Day 1
8 x 8-Repetition Maximum (RM) 
8 series of 8 half squats lifting an individualized  maximum weight
Day 2 to day 5
Rest

OTHER OUTCOMES

Blood samples: measure of acute and mid-term biomarkers of muscle damage

Muscular protection

TensLess® significantly limits the increase of both acute (myoglobin) and mid-term (creatinine and creatine kinase) biomarkers of muscle damage3,4 in the supplemented group. 

Relief from induced muscle soreness

DOMS scores decreases in the TensLess® group as soon as 1 hour after the muscle stimulation and were lowered by 28% with the supplementation compared to the placebo group. Associated muscle pain also significantly decreases in the TensLess® group, by 35% over the 4 days following the activity.

KEY OUTCOMES

  • Clinically proven effective in a 5-day supplementation 
  • Acute benefits
  • Eases joint discomfort, soreness and muscle discomfort
  • Plant-based ingredient

Applications

Commercial name
TensLess®
COMPOSITION
Mangosteen, pomegranate and elderberry extracts
ACTIVE COMPOUNDS

Ellagic acid       ≥ 13.9%
Xanthones        ≥ 9.5%
Anthocyanins  ≥ 0.5%

RECOMMENDED DOSAGE
900 mg/day
APPLICATIONS
Dietary supplements
OTHERS
No allergen, non-GMO, gluten-free, suitable for vegans

References
1 – Romain C. & cases J.; 2015; Agro Food Industry Hi Tech; 26(3):8-13
2 – Romain C. et al. 2017; Phytother. Res.; 31(11):1739-46
3 – Rodenburg J. B. et al. 1993; J. Appl. Physiol.; 19(2):93-9
4 – Hassan E. S.. 2011; J. Sports Med. Phys Fitness; 51(2):249-54

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
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Disclaimer

This website is intended to provide information about Fytexia’s ingredients, used in various dietary supplement products around the world. It is intended to provide information to food supplement professionals and is not designed for the general public. As Fytexia’s ingredients are being marketed in a large number of countries, it is the responsibility of each of our customers to ensure that the use of the ingredient and any claim made in the labeling or advertising of the ingredient comply with the applicable rules and regulations.