Prebiotics for skin health

Gut-skin axis

Characterization of the active compounds

Oliglow® is a food-based ingredient concentrated to 70% galactooligosaccharides (GOS), including 9% 4’-galactosyllactose (GL), a specific prebiotic originally isolated from mother’s milk. These soluble short-chain fibers are non-digestible and ferment in the intestine, where they contribute to a regulation of the local microflora for a healthier microbiome.

ACTIVE COMPOUNDS

Galactooligosaccharides
GOS > 70%
Galactosyllactose
4’-GL > 9%

Formulation

Recommended daily dosage: 2000 mg

Gut-skin axis: it all starts from microbiome

Oliglow® has demonstrated its benefits in rebalancing the ratio of Lactobacillus and Bifidobacteria of the gut microflora, leading to lower inflammation and oxidative stress, both of which are damaging to skin health.

Science supporting Oliglow®

The benefits of Oliglow® on skin health have been demonstrated in a clinical study compliant with the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH).

Double-blind, randomized, placebo-controlled study

DURATION

12 weeks
Measures assessed every 4 weeks

POPULATION

79 subjects
73 women / 6 men
30-69 years old

INTAKES

CAPSULES
2 x 1000 mg/day

Parameters

Usual lifestyle & diet

Outcomes

Skin barrier function
Skin sensitivity to photo-aging

Skin barrier function - hydration

Oliglow® improves the capacity of the skin to retain water, significantly improving the level of hydration of the upper layers of the epidermis.

Skin sensitivity to photo-aging

The decrease in erythema demonstrates a lower level of skin irritation, while a significant reduction of the melanin index demonstrates a lower sensitivity to sun damage.

Effect on wrinkles

Oliglow® significantly contributes to the reduction of wrinkles measured in the crow’s feet area.

KEY OUTCOMES

Rebalances the microbiome for a healthier skin
Reinforces the barrier function of the skin
Increases hydration of the upper layers of the epidermis
Decreases redness and irritation of the upper layers of the epidermis
Decreases photo-sensibility of the skin
Reduces wrinkles

Applications

Commercial name

Oliglow®

Composition

Galactooligosaccharides

ACTIVE COMPOUNDS

GOS > 70%
4’GL > 9%

RECOMMENDED DOSAGE

2 g/day

APPLICATIONS

Dry forms of dietary supplements
Instant powder or orodispersibles
Ready to drink beverages
Meal substitutes, nutritional bars, confectionery

OTHERS

Available as organic
GRAS, GMO-free, gluten-free

References
K.B. HONG et al.; Asia Pac. J. Clin. Nutr.; 2017; 26(4):613-618
M.G. Suh et al.; Prev. Nutr. Food Sci.; 2019; 24(3):321-326

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.